Today’s translational research era calls for innovative solutions to enable researchers and clinicians to build bridges between the microscopic (molecular) and macroscopic (human) scales. This requires building both transversal and vertical connections between techniques, researchers and clinicians to provide them with an optimal e-Science toolbox to tackle societal challenges related to health.
The main objective of the MoBrain Competence Center (CC) is to lower barriers for scientists to access modern e-Science solutions from micro to macro scales. MoBrain builds on grid- and cloud-based infrastructures and on the existing expertise available within WeNMR (www.wenmr.eu), N4U (neugrid4you.eu), and technology providers (NGIs and other institutions, OSG). This initiative aims to serve its user communities, related ESFRI projects (e.g. INSTRUCT) and in the long term the Human Brain Project (FET Flagship), and strengthen the EGI services offering.
By integrating molecular structural biology and medical imaging services and data, MoBrain will kick-start the development of a larger, integrated, global science virtual research environment for life and brain scientists worldwide. The mini-projects defined in MoBrain are geared toward facilitating this overall objective, each with specific objectives to reinforce existing services, develop new solutions and pave the path to global competence center and virtual research environment for translational research from molecular to brain.
There are already many services and support/training mechanisms in place that will be further developed, optimized and merged during the operation of the CC, building onto and contributing to the EGI service offering. MoBrain will produce a working environment that will be better tailored to the end user needs than any of its individual components. It will provide an extended portfolio of tools and data in a user-friendly e-laboratory, with a direct relevance for neuroscience, starting from the quantification of the molecular forces, protein folding, biomolecular interactions, drug design and treatments, improved diagnostic and the full characterization of every pathological mechanism of brain diseases through both phenomenological as well as mechanistic approaches.